CVE-2022-1521: Illumina Local Run Manager

Critical severity, CVSS 9.1. EPSS: 1.1% chance of exploitation in the next 30 days.

LRM does not implement authentication or authorization by default. A malicious actor can inject, replay, modify, and/or intercept sensitive data.

Affected products

• Illumina Local Run Manager: from 1.3, up to and including 3.1

Published 2022-06-24. Last modified 2026-06-17.